PML-RARalpha ligand-binding domain deletion mutations associated with reduced disease control and outcome after first relapse of APL.

Authors :: Schachter-Tokarz E
Kelaidi C
Cassinat B
Chomienne C
Gardin C
Raffoux E
Dombret H
Fenaux P
Gallagher R
Source :: Leukemia [Leukemia] 2010 Feb; Vol. 24 (2), pp. 473-6. Date of Electronic Publication: 2009 Oct 29.
Publication Year :: 2010

Subjects :: Adult
Child
Child, Preschool
Female
Humans
Leukemia, Promyelocytic, Acute pathology
Male
Middle Aged
Neoplasm Recurrence, Local drug therapy
Neoplasm Recurrence, Local genetics
Neoplasm Recurrence, Local pathology
Protein Structure, Tertiary
Treatment Outcome
Antineoplastic Agents therapeutic use
Leukemia, Promyelocytic, Acute drug therapy
Leukemia, Promyelocytic, Acute genetics
Oncogene Proteins, Fusion genetics
Sequence Deletion genetics
Tretinoin therapeutic use

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