DNA templated nucleophilic aromatic substitution reactions for fluorogenic sensing of oligonucleotides.

Authors :: Shibata A
Abe H
Ito M
Kondo Y
Shimizu S
Aikawa K
Ito Y
Source :: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2009 Nov 21 (43), pp. 6586-8. Date of Electronic Publication: 2009 Oct 05.
Publication Year :: 2009
Abstract: We have developed an S(N)Ar reaction-triggered fluorescence probe using a new fluorogenic compound derivatized from 7-aminocoumarin for oligonucleotides detection.

Subjects :: DNA chemistry
Fluorescent Dyes chemistry
Oligonucleotides chemistry

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