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Obstructive sleep apnea is frequent in patients with hypertensive intracerebral hemorrhage and is related to perihematoma edema.

Authors :
Pontes-Neto OM
Fernandes RM
Sander HH
da Silva LA
Mariano DC
Nobre F
Simão G
de Araujo DB
dos Santos AC
Leite JP
Source :
Cerebrovascular diseases (Basel, Switzerland) [Cerebrovasc Dis] 2010; Vol. 29 (1), pp. 36-42. Date of Electronic Publication: 2009 Nov 05.
Publication Year :
2010

Abstract

Background: Obstructive sleep apnea (OSA) is related to increased systemic inflammation and arterial hypertension. We hypothesize that OSA is frequent in patients with acute hypertensive intracerebral hemorrhage (ICH) and is related to the perihematoma edema.<br />Methods: Thirty-two non-comatose patients with a hypertensive ICH underwent polysomnography in the acute phase. Perihematoma edema volume was measured on CT scans at admission, after 24 h (early control) and after 4-5 days (late control). The Spearman coefficient (r(s)) was used for correlations.<br />Results: OSA occurred in 19 (59.4%) patients. The apnea-hypopnea index was correlated with relative edema at admission CT (r(s) = 0.40; p = 0.031), early CT (r(s) = 0.46; p = 0.011) and at late CT (r(s) = 0.59; p = 0.006).<br />Conclusions: OSA is highly frequent during the acute phase of hypertensive ICH and is related to perihematoma edema.

Details

Language :
English
ISSN :
1421-9786
Volume :
29
Issue :
1
Database :
MEDLINE
Journal :
Cerebrovascular diseases (Basel, Switzerland)
Publication Type :
Academic Journal
Accession number :
19893310
Full Text :
https://doi.org/10.1159/000255972