Back to Search
Start Over
Assessment of global left ventricular function and volumes with 320-row multidetector computed tomography: A comparison with 2D-echocardiography.
- Source :
-
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology [J Nucl Cardiol] 2010 Apr; Vol. 17 (2), pp. 225-31. Date of Electronic Publication: 2009 Dec 01. - Publication Year :
- 2010
-
Abstract
- Background: Multidetector computed tomography (MDCT) has been demonstrated as a feasible imaging modality for noninvasive assessment of coronary artery disease and left ventricular (LV) function. Recently, 320-row systems have become available with 16 cm anatomical coverage allowing image acquisition of the entire heart within a single heartbeat. The purpose of this study was to evaluate the accuracy of 320-row MDCT in the assessment of global LV function compared to two-dimensional (2D) echocardiography as the standard of reference.<br />Methods and Results: A head-to-head comparison between 320-row MDCT and 2D-echocardiography was performed in 114 patients (68 men; mean age 62 +/- 13 years) who were clinically referred for MDCT coronary angiography. The entire heart was imaged in a single heartbeat, using prospective dose modulation. LV end-diastolic volumes (LVEDV) and LV end-systolic volumes (LVESV) were determined and the LV ejection fraction (LVEF) was derived. Average LVEF was 60 +/- 10% (range 26-78%) as determined on MDCT, compared with 59 +/- 10% (range 25-77%) on 2D-echocardiography. Evaluation of LVEF by linear regression analysis showed a good correlation between MDCT and 2D-echocardiography (r(2) = .87; P < .001). Good correlations between MDCT and 2D-echocardiography were demonstrated for the assessment of LVEDV (r(2) = .91; P < .001) and LVESV (r(2) = .94; P < .001). At Bland-Altman analysis, mean differences (+/-SD) of 7.3 +/- 12.1 mL (P < .05) and 1.8 +/- 7.4 mL (P < .05) were observed between MDCT and 2D-echocardiography for LVEDV and LVESV, respectively. LVEF was slightly overestimated with MDCT (.9 +/- 3.6%; P < .05).<br />Conclusions: Accurate assessment of LV function and volumes is feasible with single heartbeat 320-row MDCT in patients referred for MDCT coronary angiography.
- Subjects :
- Aged
Cardiology methods
Coronary Artery Disease diagnosis
Female
Humans
Male
Middle Aged
Prospective Studies
Radionuclide Imaging
Regression Analysis
Reproducibility of Results
Coronary Artery Disease diagnostic imaging
Echocardiography methods
Tomography, X-Ray Computed methods
Ventricular Function, Left
Subjects
Details
- Language :
- English
- ISSN :
- 1532-6551
- Volume :
- 17
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
- Publication Type :
- Academic Journal
- Accession number :
- 19953354
- Full Text :
- https://doi.org/10.1007/s12350-009-9173-y