Engineering NIR dyes for fluorescent lifetime contrast.

Authors :: Berezin MY
Lee H
Akers W
Guo K
Goiffon RJ
Almutairi A
Fréchet JM
Achilefu S
Source :: Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference [Annu Int Conf IEEE Eng Med Biol Soc] 2009; Vol. 2009, pp. 114-7.
Publication Year :: 2009
Abstract: The excited state of an organic molecule is a crossroads which can lead to many directions, such as non-radiative emission as heat, fluorescence, intersystem crossing and phosphorescence. Due to the unpredictable nature of the excited molecular structure, manipulation of this represents significant challenges for physicists and chemists. However, the successful management of the excited state provides a number of benefits with innumerable applications to fields like photonics and medicine. One such property of the excited state with powerful ramifications in medical diagnostics is fluorescence lifetime.

Subjects :: Animals
Drug Design
Kinetics
Mice
Time Factors
Contrast Media chemistry
Fluorescent Dyes chemistry
Image Enhancement methods
Microscopy, Fluorescence methods
Spectroscopy, Near-Infrared methods
Whole Body Imaging methods

Language :: English
ISSN :: 2375-7477
Volume :: 2009
Database :: MEDLINE
Journal :: Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Publication Type :: Academic Journal
Accession number :: 19964923
Full Text :: https://doi.org/10.1109/IEMBS.2009.5334834