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Further analysis of the sequence of the S1 subunit of pertussis toxin.

Authors :
Pizza M
Bugnoli M
Pucci P
Siciliano R
Marino G
Rappuoli R
Source :
Infection and immunity [Infect Immun] 1991 Mar; Vol. 59 (3), pp. 1177-9.
Publication Year :
1991

Abstract

The two published sequences of the pertussis toxin operon differ in 3 bp in the S1 subunit gene. In this report, we provide evidence that Bordetella pertussis strains are able to produce active pertussis toxin only when they contain one of the two possible nucleotide sequences.

Details

Language :
English
ISSN :
0019-9567
Volume :
59
Issue :
3
Database :
MEDLINE
Journal :
Infection and immunity
Publication Type :
Academic Journal
Accession number :
1997420
Full Text :
https://doi.org/10.1128/iai.59.3.1177-1179.1991