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[Methylene blue therapy for vasoplegia after cardiac surgery].
- Source :
-
Anestezjologia intensywna terapia [Anestezjol Intens Ter] 2009 Jul-Sep; Vol. 41 (3), pp. 159-62. - Publication Year :
- 2009
-
Abstract
- Background: Systemic inflammatory response syndrome (SIRS) may be associated with critically decreased vascular resistance (vasoplegia syndrome) and become resistant to noradrenaline. Such a condition may be successfully treated with intravenous methylene blue.<br />Case Report: A 73-year-old patient with acute myocardial infarction and cardiogenic shock was admitted to our centre after failed percutaneous coronary interventions to the left anterior descending coronary artery and underwent emergency coronary revascularisation. After surgery, his ejection fraction was 25%. X-ray revealed pulmonary oedema. The patient became severely hypotensive with marked vasoplegia and metabolic acidosis, despite incremental doses of adrenaline and noradrenaline. 2 mg kg(-1) of methylene blue was administered, which quickly stabilized the patient's general condition.<br />Conclusion: Methylene blue applied to vasoplegic patients can effectively increase systemic vascular resistance and restore satisfactory organ perfusion.
- Subjects :
- Acidosis drug therapy
Acidosis etiology
Aged
Cardiac Surgical Procedures adverse effects
Humans
Hypotension drug therapy
Hypotension etiology
Male
Myocardial Infarction surgery
Pulmonary Edema drug therapy
Pulmonary Edema etiology
Severity of Illness Index
Shock, Cardiogenic surgery
Vascular Resistance drug effects
Vasoplegia etiology
Enzyme Inhibitors therapeutic use
Methylene Blue therapeutic use
Vasoplegia drug therapy
Subjects
Details
- Language :
- Polish
- ISSN :
- 0209-1712
- Volume :
- 41
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Anestezjologia intensywna terapia
- Publication Type :
- Academic Journal
- Accession number :
- 19999604