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[Microcalorimetric investigation of two cephalosporins on colon bacteria activity].
- Source :
-
Yao xue xue bao = Acta pharmaceutica Sinica [Yao Xue Xue Bao] 2009 Oct; Vol. 44 (10), pp. 1127-30. - Publication Year :
- 2009
-
Abstract
- The effects of cephradinum and ceftazidime on the metabolism of Escherichia coli (E. coli) DH5alpha was determined by microcalorimetry. The microbial activity was recorded as power-time curves through an ampoule method with a TAM Air Isothermal Microcalorimeter at 37 degrees C. The parameters such as the growth rate constant (k), inhibitory ratio (I), the maximum power output (Pm) and the time (tm) corresponding to the maximum power output were calculated. The results show that the ceftazidime has a better inhibitory effect on E. coli DH5alpha than cephradinum.
- Subjects :
- Anti-Bacterial Agents administration & dosage
Ceftazidime administration & dosage
Cephradine administration & dosage
Escherichia coli growth & development
Escherichia coli metabolism
Microbial Sensitivity Tests
Anti-Bacterial Agents pharmacology
Calorimetry methods
Ceftazidime pharmacology
Cephradine pharmacology
Escherichia coli drug effects
Subjects
Details
- Language :
- Chinese
- ISSN :
- 0513-4870
- Volume :
- 44
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Yao xue xue bao = Acta pharmaceutica Sinica
- Publication Type :
- Academic Journal
- Accession number :
- 20055136