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[Detection of selected diuretics in biological fluids by chromatography mass spectrometry].

Authors :
Alikhodzhaeva MI
Simonov EA
Kirichek AV
Popkov VA
Source :
Sudebno-meditsinskaia ekspertiza [Sud Med Ekspert] 2009 Sep-Oct; Vol. 52 (5), pp. 27-9.
Publication Year :
2009

Abstract

Modified methods for the detection and measurement of furosemide and spironolactone in biological fluids has been developed based on gas chromatography mass spectrometry. Optimal conditions for chromatography are described for the determination of the diuretic agents of interest. The proposed methods were verified by analysing urine samples obtained from patients with chronic cardiac insufficiency.

Details

Language :
Russian
ISSN :
0039-4521
Volume :
52
Issue :
5
Database :
MEDLINE
Journal :
Sudebno-meditsinskaia ekspertiza
Publication Type :
Academic Journal
Accession number :
20058847