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[Relationship of fatty liver with HBV infection, hyperlipidemia and abnormal alanine aminotransferase].
- Source :
-
Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology [Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi] 2009 Apr; Vol. 23 (2), pp. 141-3. - Publication Year :
- 2009
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Abstract
- Objective: To investigate the prevalence of fatty liver in Guangzhou and its relation to hepatitis B virus (HBV) infection, hyperlipidemia and abnormal alanine aminotransferase (ALT).<br />Methods: A retrospective analysis was made on clinical data of 4365 participants who received health check-up in our hospital.<br />Results: The prevalence of fatty liver was 18.2%, 19.2% in males and 17.1% in females, respectively. There was no significant difference between males and females (P = 0.07). Among 793 subjects with fatty liver, 440 were males and 353 were females. The prevalence of fatty liver was 16.7% in HBV infection group and 18.3% in the group without HBV infection, no significant difference was seen between these two groups (P = 0.45). The prevalence of fatty liver was 42.1% in hyperlipidemia group, and 11.6% in the group with normal serum triglyceride (TG) and total cholesterol (TC), respectively, there was a significant difference between these two groups (P < 0.05). The abnormal ALT was seen in 32.5% of the fattty liver group, which was significantly higher than that (8.6%) in the group without fatty liver (P < 0.05).<br />Conclusions: The prevalence of fatty liver was not significantly different between males and females in Guangzhou. Fatty liver was not related with HBV infection but closely related with age and hyperlipidemia. Fatty liver was a common cause of abnormal ALT.
- Subjects :
- Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
China epidemiology
Fatty Liver enzymology
Fatty Liver epidemiology
Female
Hepatitis B blood
Hepatitis B virus isolation & purification
Humans
Male
Middle Aged
Retrospective Studies
Young Adult
Alanine Transaminase blood
Fatty Liver blood
Fatty Liver virology
Hepatitis B virology
Hepatitis B virus physiology
Hyperlipidemias blood
Subjects
Details
- Language :
- Chinese
- ISSN :
- 1003-9279
- Volume :
- 23
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology
- Publication Type :
- Academic Journal
- Accession number :
- 20104761