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Long-lasting control of triple-negative metastatic breast cancer with the novel drug combination ixabepilone and capecitabine--case report.
- Source :
-
Onkologie [Onkologie] 2010; Vol. 33 (1-2), pp. 53-6. Date of Electronic Publication: 2010 Jan 05. - Publication Year :
- 2010
-
Abstract
- Background: The optimal duration of ixabepilone and capecitabine chemotherapy combination is currently not known and will most likely be patient-specific based on efficacy, toxicity, quality of life, and patient preference.<br />Case Report: We report an extremely long duration of chemotherapy with ixabepilone and capecitabine (42 cycles) in a patient with triple-negative metastatic breast cancer previously treated with anthracyclines and taxanes. Partial remission was achieved, and acceptable toxicity was observed.<br />Conclusions: This report adds to the pool of knowledge regarding the use of this important new metastatic breast cancer regimen, especially with respect to the optimal duration of its use.<br /> ((c) 2010 S. Karger AG, Basel.)
- Subjects :
- Antineoplastic Combined Chemotherapy Protocols adverse effects
Biomarkers, Tumor genetics
Breast Neoplasms genetics
Capecitabine
Carcinoma, Ductal drug therapy
Carcinoma, Ductal genetics
Carcinoma, Papillary drug therapy
Carcinoma, Papillary genetics
Combined Modality Therapy
Deoxycytidine administration & dosage
Deoxycytidine adverse effects
Deoxycytidine analogs & derivatives
Disease Progression
Dose-Response Relationship, Drug
Drug Administration Schedule
Epothilones administration & dosage
Epothilones adverse effects
Female
Fluorouracil administration & dosage
Fluorouracil adverse effects
Fluorouracil analogs & derivatives
Follow-Up Studies
Humans
Long-Term Care
Lung Neoplasms drug therapy
Middle Aged
Neoplasms, Second Primary genetics
Randomized Controlled Trials as Topic
Receptor, ErbB-2 genetics
Receptors, Estrogen genetics
Receptors, Progesterone genetics
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Breast Neoplasms drug therapy
Carcinoma, Ductal secondary
Carcinoma, Papillary secondary
Lung Neoplasms secondary
Neoplasms, Second Primary drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1423-0240
- Volume :
- 33
- Issue :
- 1-2
- Database :
- MEDLINE
- Journal :
- Onkologie
- Publication Type :
- Academic Journal
- Accession number :
- 20164663
- Full Text :
- https://doi.org/10.1159/000264615