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[Role of 125I seed implantation in treatment of unresectable pancreatic cancer].
- Source :
-
Zhonghua yi xue za zhi [Zhonghua Yi Xue Za Zhi] 2010 Jan 12; Vol. 90 (2), pp. 92-5. - Publication Year :
- 2010
-
Abstract
- Objective: To study the role of (125)I seed implantation in the treatment of unresectable pancreatic cancer.<br />Methods: From April 2004 to march 2006, 66 untreated patients with locally advanced pancreatic cancer (LAPC) were randomized into two groups: Group A: (125)I seeds implantation (n = 31) and Group B: control (n = 34). The objective tumor response, clinical benefit response, toxicity, complications and survival of two groups were observed.<br />Results: In Group A, the overall response rate (PR + NC) was 80.6%. Clinical benefit response rate was 54.8%. No toxicity was observed. Gastrointestinal hemorrhage and pancreatic fistula occurred in 1 patient respectively in Group A. The survival rates of 6 and 12 months were 56.0% vs 31.4% and 16.8% vs 2.9% respectively in two groups (P < 0.05). The median survival time of two groups was 8.0 months vs 4.0 months (P < 0.05).<br />Conclusion: (125)I seed implantation is a simple, safe and effective method in the treatment of locally advanced pancreatic cancer.
Details
- Language :
- Chinese
- ISSN :
- 0376-2491
- Volume :
- 90
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Zhonghua yi xue za zhi
- Publication Type :
- Academic Journal
- Accession number :
- 20356489