Back to Search
Start Over
Microarray analysis of the liver in metallothionein-III null mice treated with cadmium.
- Source :
-
The Journal of toxicological sciences [J Toxicol Sci] 2010 Apr; Vol. 35 (2), pp. 271-3. - Publication Year :
- 2010
-
Abstract
- In order to elucidate the effect of metallothionein (MT)-III on hepatic gene expression altered by cadmium (Cd), we examined gene expression patterns in the liver of MT-III null mice and wild-type mice after Cd injection using a DNA microarray containing 35,852 genes. In a comparison between Cd-injected MT-III null mice and Cd-injected wild-type mice, 9 genes were found to be up-regulated and 28 genes-including serum amyloid A1 (SAA-1) and SAA-2--were down-regulated.
Details
- Language :
- English
- ISSN :
- 1880-3989
- Volume :
- 35
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- The Journal of toxicological sciences
- Publication Type :
- Academic Journal
- Accession number :
- 20371981
- Full Text :
- https://doi.org/10.2131/jts.35.271