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Hepatic artery resistance in children with obesity and fatty liver.

Authors :: Hizli S
Koçyigit A
Arslan N
Tuncel SA
Demircioglu F
Cakmakçi H
Büyükgebiz B
Source :: Indian journal of pediatrics [Indian J Pediatr] 2010 Apr; Vol. 77 (4), pp. 407-11. Date of Electronic Publication: 2010 Mar 19.
Publication Year :: 2010
Abstract: Objective: The present study assessed whether there is a correlation between hepatic artery resistive index (HARI) and increase of body mass index and hepatosteatosis grading in children with non-alcoholic fatty liver disease (NAFLD) reflecting hemodynamic effects of hepatosteatosis.<br />Methods: Thirty three healthy children [body mass index(BMI): mean+/- standart deviation(SD), min-max: 20.1+/-1.14(18.5-23.7), 33 overweight [BMI:25.1+/-2.2 (18.5-23.7)] and 66 obese [BMI:31.1+/-2(25.6-40)] adolescents were enrolled into the study. To search the relation of HARI with fatty liver degree, study subjects subdivided into groups according to their degree of fatty liver at ultrasonography(US).<br />Results: Increase of HARI was correlated with increase in BMI (p<0.0001, r=0.533). Increase of HARI was well correlated with increase in degree of fatty liver (p<0.0001, r=0.630).<br />Conclusion: The present study results suggest that there are positive correlations of HARI with BMI and hepatosteatosis grade in obese children with NAFLD. HARI may be a candidate parameter to determine early alarming hemodynamic changes in hepatic tissue of obese children with fatty liver before development of severe stages NAFLD.