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Lyme neuroborreliosis: aetiology and diagnosis of facial palsy in children from Tyrol.
- Source :
-
Klinische Padiatrie [Klin Padiatr] 2010 Sep; Vol. 222 (5), pp. 302-7. Date of Electronic Publication: 2010 May 07. - Publication Year :
- 2010
-
Abstract
- Background: Lyme neuroborreliosis (LNB) is the second most common manifestation of Borrelia burgdorferi sensu lato (s. l.) infection in Europe. LNB is difficult to differentiate from other aetiologies of aseptic meningitis. Diagnostic criteria for LNB in children are not established. Therfore, based on the epidemiology of LNB in children from Tyrol, the aim of our study was to point out the necessity of a clear definition of pediatric LNB to avoid underdiagnosis and overtreatment.<br />Patients and Methods: All medical charts of patients presented with acute peripheral facial palsy from January 2002 to December 2005 were reviewed. The patients were rediagnosed according to the criteria of the German Society of Neurology (DGN).<br />Results: We identified 66 patients with peripheral facial palsy. 30 children were handled as B. burgdorferi s. l. infection. 5 patients were overtreated with antibiotic therapy. After reevaluation according to the DGN criteria 7 cases were reclassified as possible, 16 cases as probable and 7 cases as confirmed LNB.<br />Conclusions: Utilization of the established DGN criteria for pediatric LNB might help to elucidate the propability of LNB. Prospective studies are required to establish a classification system. A diagnostic tool, based on laboratory and clinical data, should avoid overtreatment of pediatric LNB.<br /> (Georg Thieme Verlag KG Stuttgart, New York.)
- Subjects :
- Adolescent
Antibodies, Bacterial blood
Austria
Borrelia burgdorferi Group immunology
Child
Child, Preschool
Cross-Sectional Studies
Diagnosis, Differential
Enzyme-Linked Immunosorbent Assay
Facial Paralysis epidemiology
Female
Humans
Immunoblotting
Incidence
Infant
Lyme Neuroborreliosis epidemiology
Male
Meningitis, Aseptic epidemiology
Retrospective Studies
Facial Paralysis etiology
Lyme Neuroborreliosis diagnosis
Meningitis, Aseptic etiology
Subjects
Details
- Language :
- English
- ISSN :
- 1439-3824
- Volume :
- 222
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Klinische Padiatrie
- Publication Type :
- Academic Journal
- Accession number :
- 20455197
- Full Text :
- https://doi.org/10.1055/s-0030-1249091