Back to Search Start Over

Repitools: an R package for the analysis of enrichment-based epigenomic data.

Authors :
Statham AL
Strbenac D
Coolen MW
Stirzaker C
Clark SJ
Robinson MD
Source :
Bioinformatics (Oxford, England) [Bioinformatics] 2010 Jul 01; Vol. 26 (13), pp. 1662-3. Date of Electronic Publication: 2010 May 10.
Publication Year :
2010

Abstract

Summary: Epigenetics, the study of heritable somatic phenotypic changes not related to DNA sequence, has emerged as a critical component of the landscape of gene regulation. The epigenetic layers, such as DNA methylation, histone modifications and nuclear architecture are now being extensively studied in many cell types and disease settings. Few software tools exist to summarize and interpret these datasets. We have created a toolbox of procedures to interrogate and visualize epigenomic data (both array- and sequencing-based) and make available a software package for the cross-platform R language.<br />Availability: The package is freely available under LGPL from the R-Forge web site (http://repitools.r-forge.r-project.org/)<br />Contact: mrobinson@wehi.edu.au.

Details

Language :
English
ISSN :
1367-4811
Volume :
26
Issue :
13
Database :
MEDLINE
Journal :
Bioinformatics (Oxford, England)
Publication Type :
Academic Journal
Accession number :
20457667
Full Text :
https://doi.org/10.1093/bioinformatics/btq247