Novoamauromine and ent-Cycloechinulin: two new diketopiperazine derivatives from Aspergillus novofumigatus.

Authors :: Ishikawa K
Hosoe T
Itabashi T
Wakana D
Takizawa K
Yaguchi T
Kawai K
Source :: Chemical & pharmaceutical bulletin [Chem Pharm Bull (Tokyo)] 2010 May; Vol. 58 (5), pp. 717-9.
Publication Year :: 2010
Abstract: Two new diketopiperazine metabolites, novoamauromine (1) and ent-cycloechinulin (2) have been isolated from Aspergillus novofumigatus CBS117520. The structures of 1 and 2 were established on the basis of spectroscopic and chemical investigation, including a detailed comparison of the spectroscopic and physico-chemical data of amauromine (3) and cycloechinulin (4).

Subjects :: Cell Line, Tumor
Chromatography, Liquid
Fungi drug effects
Humans
Magnetic Resonance Spectroscopy
Microbial Sensitivity Tests
Molecular Structure
Antifungal Agents chemistry
Antifungal Agents pharmacology
Antineoplastic Agents chemistry
Antineoplastic Agents pharmacology
Aspergillus chemistry
Diketopiperazines chemistry

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