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Bone mineral density and respiratory muscle strength in male individuals with mental retardation (with and without Down Syndrome).
- Source :
-
Research in developmental disabilities [Res Dev Disabil] 2010 Nov-Dec; Vol. 31 (6), pp. 1585-9. Date of Electronic Publication: 2010 Jun 11. - Publication Year :
- 2010
-
Abstract
- The purpose of this study was to assess the respiratory muscle strength (RMS) in individuals with mental retardation (MR), with or without Down Syndrome (DS), and its association with bone mineral density (BMD). Forty-five male individuals (15 with DS, 15 with mental retardation (MR) and 15 apparently healthy controls), aged 20-35, participated in this study. Subject assessment included pulmonary function tests, RMS (maximal inspiratory pressure, MIP, and maximal expiratory pressure, MEP) and BMD of the second and fourth lumbar vertebrae. ANOVA was used to test differences amongst groups. Tukey post hoc test was utilized when significant differences were detected with ANOVA. Bivariate correlation for BMD and respiratory muscle strength was calculated with Pearson's coefficient of correlation. Individuals with MR, both with and without DS, have lower FEV1, FVC, MIP and MEP (p<0.001) compared to controls. Individuals with DS also had lower BMD, which was associated with lower MIP and MEP. Hypotonia, sedentary lifestyle and obesity are factors that may explain lower MIP and MEP in DS. Strategies to increase RMS could decrease the risk of osteoporosis in the DS population.<br /> (Copyright © 2010 Elsevier Ltd. All rights reserved.)
- Subjects :
- Adult
Down Syndrome physiopathology
Humans
Intellectual Disability physiopathology
Life Style
Male
Muscle Hypotonia epidemiology
Muscle Hypotonia physiopathology
Osteoporosis physiopathology
Respiratory Function Tests
Risk Factors
Young Adult
Bone Density
Down Syndrome epidemiology
Intellectual Disability epidemiology
Muscle Strength physiology
Osteoporosis epidemiology
Respiratory Muscles physiology
Subjects
Details
- Language :
- English
- ISSN :
- 1873-3379
- Volume :
- 31
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Research in developmental disabilities
- Publication Type :
- Academic Journal
- Accession number :
- 20541908
- Full Text :
- https://doi.org/10.1016/j.ridd.2010.05.003