Surface biocompatible modification of polypropylene by entrapment of polypropylene-block-poly(vinylpyrrolidone).

Authors :: Xu M
Qiu J
Lin Y
Shi X
Chen H
Xiao T
Source :: Colloids and surfaces. B, Biointerfaces [Colloids Surf B Biointerfaces] 2010 Oct 15; Vol. 80 (2), pp. 200-5. Date of Electronic Publication: 2010 Jun 15.
Publication Year :: 2010
Abstract: A macromolecular surface modifier, namely polypropylene-block-poly(vinylpyrrolidone) copolymer, could diffuse preferably onto the surface and effectively increased the biocompatibility of PP. The blood and cell compatibilities of PP and PP-b-PVP/PP blend films were evaluated by determination of the extent of platelet adsorption, plasma recalcification time, hemolysis rate and cell proliferation using smooth muscle cells from rabbit aorta. The results revealed that the blood and cell compatibilities of PP were improved significantly by entrapment of a few PP-b-PVP copolymers in PP.<br /> (Copyright (c) 2010 Elsevier B.V. All rights reserved.)

Subjects :: Animals
Aorta cytology
Biocompatible Materials chemical synthesis
Cell Proliferation drug effects
Hemolysis drug effects
Microscopy, Electron, Scanning
Myocytes, Smooth Muscle cytology
Myocytes, Smooth Muscle drug effects
Polymers chemical synthesis
Rabbits
Surface Properties
Biocompatible Materials adverse effects
Biocompatible Materials chemistry
Membranes, Artificial
Polymers adverse effects
Polymers chemistry
Polypropylenes chemistry
Pyrrolidines chemistry

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