Two new amide alkaloids from the flower of Datura metel L.

Authors :: Yang BY
Xia YG
Wang QH
Dou DQ
Kuang HX
Source :: Fitoterapia [Fitoterapia] 2010 Dec; Vol. 81 (8), pp. 1003-5. Date of Electronic Publication: 2010 Jun 28.
Publication Year :: 2010
Abstract: Two new amide alkaloids were isolated from the alkaloidal fraction of Datura metel L. Their structures were elucidated as (E)-methyl 4-(3-(4-hydroxyphenyl)-N-methylacrylamido) butanoate and 6,7-dimethyl-1-D-ribityl-quinoxaline-2,3(1H,4H)-dione-5'-O-β-D-glucopyranoside on the basis of spectroscopic methods including HRESIMS, 1D and 2D NMR. Tropane alkaloids have for a long time been considered as characteristic ingredients of D. metel. However, the presence of amide alkaloids in D. metel was reported for the first time in this study.<br /> (Crown Copyright © 2010. Published by Elsevier B.V. All rights reserved.)