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Seroprevalence of Toxoplasma gondii antibodies in North Indian blood donors: implications for transfusion transmissible toxoplasmosis.
- Source :
-
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis [Transfus Apher Sci] 2010 Aug; Vol. 43 (1), pp. 37-40. - Publication Year :
- 2010
-
Abstract
- Introduction: Transfusion transmitted Toxoplasma gondii (T. gondii) can result in significant clinical consequences in immunocompromised and multiply transfused patients, pregnant women and fetus etc. Anti-T. gondii seroprevalence, specifically IgM antibodies reflect the risk of transfusion transmission.<br />Methods: Four hundred and ninety-three blood donors in a tertiary care hospital in North India were screened for IgG and IgM anti-T. gondii antibodies by enzyme linked immunosorbent assay (ELISA).<br />Results: The prevalence of IgG and IgM anti-T. gondii antibodies was 51.8% and 5% respectively. The prevalence was higher in females (M=51.6%, F=89.2%) and in replacement donors (replacement donors=63.2%, voluntary donors=33.5%).<br />Conclusion: The donor population constitutes a significant risk of transfusion transmitted toxoplasmosis. Effective strategies are required to prevent transfusion transmitted toxoplasmosis.<br /> ((c) 2010 Elsevier Ltd. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1473-0502
- Volume :
- 43
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis
- Publication Type :
- Academic Journal
- Accession number :
- 20605111
- Full Text :
- https://doi.org/10.1016/j.transci.2010.05.004