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Treatment of acyclovir-resistant herpes simplex virus with continuous infusion of high-dose acyclovir in hematopoietic cell transplant patients.
- Source :
-
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation [Biol Blood Marrow Transplant] 2011 Feb; Vol. 17 (2), pp. 259-64. Date of Electronic Publication: 2010 Jul 06. - Publication Year :
- 2011
-
Abstract
- Infection because of herpes simplex virus (HSV) that is resistant to acyclovir (ACV) poses treatment challenges in hematopoietic cell transplant (HCT) patients. We present a series of patients with ACV-resistant HSV following HCT who were successfully treated with continuous infusion high-dose ACV after failing standard treatment regimens for ACV-resistant HSV.<br /> (Copyright © 2011 American Society for Blood and Marrow Transplantation. Published by Elsevier Inc. All rights reserved.)
- Subjects :
- Acyclovir adverse effects
Adult
Antiviral Agents adverse effects
Antiviral Agents therapeutic use
Drug Resistance, Multiple, Viral
Female
Humans
Immunocompromised Host
Infusions, Intravenous
Male
Middle Aged
Simplexvirus isolation & purification
Treatment Outcome
Acyclovir administration & dosage
Acyclovir therapeutic use
Antiviral Agents administration & dosage
Drug Resistance, Viral
Hematopoietic Stem Cell Transplantation
Herpes Simplex drug therapy
Simplexvirus drug effects
Subjects
Details
- Language :
- English
- ISSN :
- 1523-6536
- Volume :
- 17
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
- Publication Type :
- Academic Journal
- Accession number :
- 20615475
- Full Text :
- https://doi.org/10.1016/j.bbmt.2010.06.020