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RETRACTED: Antitumor activity of bortezomib in human cancer cells with acquired resistance to anti-epidermal growth factor receptor tyrosine kinase inhibitors.
- Source :
-
Lung cancer (Amsterdam, Netherlands) [Lung Cancer] 2011 Mar; Vol. 71 (3), pp. 283-90. - Publication Year :
- 2011
-
Abstract
- This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief Concern has been raised about the duplication of the β-Actin protein blot in the western blots that are in Figure 3A and Figure 4C. The authors have been asked to provide an acceptable explanation for this and – after initial denial and being presented with an independent evaluation noted that the western blot for β-Actin in Figure 3A was erroneously uploaded as a partial duplication of the β-Actin western blot in Figure 4C. According to the authors, this mistake was due to the fact that both Figure 3A and Figure 4C are representing the same experiment with only different protein species presented in the two Figures and with the loading control β-Actin that is presented in both Figures. The Editor-in-Chief of the journal therefore feels that the findings of the manuscript cannot be relied upon and that the article needs to be retracted. All authors agree with this retraction and deeply regret these errors and apologize to the editorial board and readers for any inconvenience caused.<br /> (Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.)
- Subjects :
- Animals
Apoptosis drug effects
Bortezomib
Cell Line, Tumor
Cell Proliferation drug effects
Erlotinib Hydrochloride
Female
Gefitinib
Humans
Mice
Mice, Inbred BALB C
Mice, Nude
Quinazolines pharmacology
Signal Transduction drug effects
Xenograft Model Antitumor Assays
Antineoplastic Agents pharmacology
Boronic Acids pharmacology
Carcinoma, Non-Small-Cell Lung physiopathology
Drug Resistance, Neoplasm drug effects
Drug Resistance, Neoplasm genetics
Protein Kinase Inhibitors pharmacology
Pyrazines pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 1872-8332
- Volume :
- 71
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Lung cancer (Amsterdam, Netherlands)
- Publication Type :
- Academic Journal
- Accession number :
- 20619923
- Full Text :
- https://doi.org/10.1016/j.lungcan.2010.06.005