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Incidence of renal replacement therapy (RRT) in the diabetic compared with the non-diabetic population in a German region, 2002-08.
- Source :
-
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association [Nephrol Dial Transplant] 2011 Jan; Vol. 26 (1), pp. 264-9. Date of Electronic Publication: 2010 Jul 11. - Publication Year :
- 2011
-
Abstract
- Background: This study was conducted to estimate incidences of renal replacement therapy (RRT) in the diabetic and non-diabetic populations in Germany, as well as relative and attributable risks of RRT due to diabetes.<br />Methods: Using the data of a regional dialysis centre (region population of 310 000), we assessed all incident RRT patients aged 30 years or older in 2002-08. We estimated sex- and age-specific and -standardized incidences of RRT in the diabetic and non-diabetic populations, which were estimated by applying diabetes prevalences from a population-based study, and relative and attributable risks due to diabetes.<br />Results: Of all subjects with incident RRT (n = 544), 49.6% had diabetes. Fifty-eight percent were male, mean age (SD) was 70.3 years (11.4 years). Incidences per 100 000 person-years (standardized to the 2004 German population) in the diabetic and the non-diabetic populations were 213.7 [95% confidence interval (95% CI), 159.5-267.8] and 26.9 (95% CI, 22.5-31.3) in men and 130.2 (95% CI, 65.6-194.9) and 16.4 (95% CI, 13.5-19.3) in women, respectively. Standardized relative risks were 7.9 (5.9-10.8) in men and 8.0 (4.7-13.5) in women. There was a significant interaction between age and diabetes, with lower relative risks in higher ages. Attributable risks among diabetic individuals were 0.87 in men and women, and population-attributable risks were 0.41 and 0.35 in men and women, respectively.<br />Conclusions: In this population-based study in a German region, we found the relative risk of RRT in the estimated adult diabetic population to be 8-fold increased compared with the non-diabetic population. A high proportion of the RRT risk can be attributed to diabetes in the diabetic as well as in the whole population.
- Subjects :
- Adult
Aged
Aged, 80 and over
Diabetes Mellitus epidemiology
Diabetes Mellitus mortality
Female
Germany epidemiology
Humans
Incidence
Kidney Failure, Chronic mortality
Kidney Failure, Chronic therapy
Kidney Transplantation
Male
Middle Aged
Registries
Renal Dialysis
Survival Rate
Treatment Outcome
Diabetes Complications epidemiology
Diabetes Mellitus therapy
Kidney Failure, Chronic complications
Renal Replacement Therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1460-2385
- Volume :
- 26
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
- Publication Type :
- Academic Journal
- Accession number :
- 20624774
- Full Text :
- https://doi.org/10.1093/ndt/gfq398