[Tetragametic chimerism: Case report].

Authors :: Loriaux A
Boulet S
Delorme V
Althuser M
Giroud Lathuile C
Grego S
Amblard F
Dupuis C
Schaal JP
Jouk PS
Source :: Journal de gynecologie, obstetrique et biologie de la reproduction [J Gynecol Obstet Biol Reprod (Paris)] 2011 Feb; Vol. 40 (1), pp. 77-80. Date of Electronic Publication: 2010 Aug 07.
Publication Year :: 2011
Abstract: We report the third case of spontaneous monochorionic dizygous pregnancy, discovered on foetal sex discordance. Blood group testing on the female twin revealed a hematopoietic chimera. The mechanism of monochorionic dizygous formation could be the fusion of two independent zygotes at a late morula stage. A single placental mass with vascular anastomosis then develops. Stem cells exchanged during early foetal life can thus lead to chimeras, in similar conditions to stem cell transfusion in adults. Immaturity of the foetal immune system allows cell graft in the other twin's marrow. Assisted reproductive procedures are believed to promote such pregnancies.<br /> (Copyright Â© 2010 Elsevier Masson SAS. All rights reserved.)

Subjects :: Adult
Female
Humans
Pregnancy
Chimerism
Pregnancy Complications
Pregnancy, Multiple

Language :: French
ISSN :: 1773-0430
Volume :: 40
Issue :: 1
Database :: MEDLINE
Journal :: Journal de gynecologie, obstetrique et biologie de la reproduction
Publication Type :: Academic Journal
Accession number :: 20692777
Full Text :: https://doi.org/10.1016/j.jgyn.2010.06.011