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[Children's Langerhans cell histiocytosis, diagnostic problems].
- Source :
-
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi [Rev Med Chir Soc Med Nat Iasi] 2010 Apr-Jun; Vol. 114 (2), pp. 424-7. - Publication Year :
- 2010
-
Abstract
- Langerhans cell histiocytosis is a group of idiopathic disorders characterized by the proliferation of cells of the mononuclear phagocyte system and the dendritic cell system. From the clinical point of view there are 3 forms of histiocytosis encountered in child pathology: acute, disseminated called Abt-Letterer-Siwe (it usually affects children under 2 years of age), eosinophilic granuloma and the intermediate clinical form called Hand-Schuller-Christian disease. We present the case of a premature born child that had, even from the day she was born, a rash disseminated on the entire surface of the body associated with enlarged lymph nodes, hepatosplenomegaly and thrombocytopenia. The diagnosis of Langerhans cell Histiocytosis is difficult to establish and this case is an example that confirms it. Therefore, we present the difficulties in diagnosing this case and its particular evolution.
- Subjects :
- Diagnosis, Differential
Exanthema etiology
Fatal Outcome
Female
Hepatomegaly etiology
Histiocytosis, Langerhans-Cell complications
Histiocytosis, Langerhans-Cell therapy
Humans
Infant, Newborn
Infant, Premature
Lymphatic Diseases etiology
Risk Factors
Splenomegaly etiology
Histiocytosis, Langerhans-Cell diagnosis
Subjects
Details
- Language :
- Romanian; Moldavian; Moldovan
- ISSN :
- 0048-7848
- Volume :
- 114
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi
- Publication Type :
- Academic Journal
- Accession number :
- 20700979