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Dietary monounsaturated fatty acids appear not to provide cardioprotection.

Authors :
Degirolamo C
Rudel LL
Source :
Current atherosclerosis reports [Curr Atheroscler Rep] 2010 Nov; Vol. 12 (6), pp. 391-6.
Publication Year :
2010

Abstract

Dietary interventions have been consistently proposed as a part of a comprehensive strategy to lower the incidence and severity of coronary heart disease (CHD), in the process providing long-term cardioprotection. Replacement of dietary saturated fatty acids (SFA) with higher intakes of monounsaturated fatty acids (MUFA) and polyunsaturated fatty acids (PUFA) has been reported to be inversely associated with risk of CHD. The observed lower incidence of CHD among populations consuming a Mediterranean-type diet, mainly enriched in MUFA from olive oil, has long supported the belief that MUFA are an optimal substitution for SFA. However, both epidemiologic and interventional studies suggest that although substituting MUFA-rich foods for SFA-rich foods in the diet can potentially lower total plasma cholesterol concentrations, this substitution does not lower the extent of coronary artery atherosclerosis. In addition, although recent evidence suggests that the source of MUFA (animal fat vs vegetable oils) may differentially influence the correlation between MUFA intake and CHD mortality, animal studies suggest that neither source is cardioprotective.

Details

Language :
English
ISSN :
1534-6242
Volume :
12
Issue :
6
Database :
MEDLINE
Journal :
Current atherosclerosis reports
Publication Type :
Academic Journal
Accession number :
20725810
Full Text :
https://doi.org/10.1007/s11883-010-0133-4