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Effect of caloric and non-caloric sweet reward solutions on thermal facial operant conditioning.

Authors :
Nolan TA
Caudle RM
Neubert JK
Source :
Behavioural brain research [Behav Brain Res] 2011 Jan 20; Vol. 216 (2), pp. 723-5. Date of Electronic Publication: 2010 Aug 24.
Publication Year :
2011

Abstract

Sweet solutions are commonly used in animal research to deliver drugs to test for addictive capacity and efficacy. In this study we compared the effects of a range of sucrose and saccharin concentrations on the performance of an operant assay. Our findings demonstrate that across a range of sucrose solutions some produce a success ratio which could mistakenly be labeled allodynic demonstrating the importance of choosing the correct reward solution.<br /> (Copyright © 2010 Elsevier B.V. All rights reserved.)

Details

Language :
English
ISSN :
1872-7549
Volume :
216
Issue :
2
Database :
MEDLINE
Journal :
Behavioural brain research
Publication Type :
Academic Journal
Accession number :
20797411
Full Text :
https://doi.org/10.1016/j.bbr.2010.08.023