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International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 3: extraprostatic extension, lymphovascular invasion and locally advanced disease.
- Source :
-
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc [Mod Pathol] 2011 Jan; Vol. 24 (1), pp. 26-38. Date of Electronic Publication: 2010 Aug 27. - Publication Year :
- 2011
-
Abstract
- The International Society of Urological Pathology Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens in Boston made recommendations regarding the standardization of pathology reporting of radical prostatectomy specimens. Issues relating to extraprostatic extension (pT3a disease), bladder neck invasion, lymphovascular invasion and the definition of pT4 were coordinated by working group 3. It was agreed that prostate cancer can be categorized as pT3a in the absence of adipose tissue involvement when cancer bulges beyond the contour of the gland or beyond the condensed smooth muscle of the prostate at posterior and posterolateral sites. Extraprostatic extension can also be identified anteriorly. It was agreed that the location of extraprostatic extension should be reported. Although there was consensus that the amount of extraprostatic extension should be quantitated, there was no agreement as to which method of quantitation should be employed. There was overwhelming consensus that microscopic urinary bladder neck invasion by carcinoma should be reported as stage pT3a and that lymphovascular invasion by carcinoma should be reported. It is recommended that these elements are considered in the development of practice guidelines and in the daily practice of urological surgical pathology.
- Subjects :
- Adenocarcinoma classification
Adenocarcinoma surgery
Boston
Humans
Internationality
Lymph Nodes pathology
Lymphatic Metastasis
Male
Neoplasm Invasiveness
Neoplasm Staging
Prognosis
Prostatic Neoplasms classification
Prostatic Neoplasms surgery
Societies, Medical
Urinary Bladder pathology
Adenocarcinoma pathology
Prostatectomy methods
Prostatic Neoplasms pathology
Specimen Handling methods
Subjects
Details
- Language :
- English
- ISSN :
- 1530-0285
- Volume :
- 24
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
- Publication Type :
- Academic Journal
- Accession number :
- 20802467
- Full Text :
- https://doi.org/10.1038/modpathol.2010.158