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Posterior segment ophthalmic complications of aplastic anemia.
- Source :
-
Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye [Ophthalmic Surg Lasers Imaging] 2010 Jun 30; Vol. 41 Online. Date of Electronic Publication: 2010 Jun 30. - Publication Year :
- 2010
-
Abstract
- Three patients with aplastic anemia were evaluated by the ophthalmology service within 2 months of the aplastic anemia diagnosis for bilateral visual loss. The mean age of diagnosis of aplastic anemia was 14.3 years (range: 5 to 19 years) and the mean follow-up was 25 months (range: 15 to 44 months). All 6 eyes demonstrated choroidal ischemia and vitreous hemorrhage. Pars plana vitrectomy was performed in four eyes of two patients for non-clearing vitreous hemorrhage; one patient was observed. Successful anatomic outcomes were achieved in 3 of 4 eyes that underwent vitrectomy. Initial visual acuity ranged from 20/80 to bare light perception and final visual acuity ranged from 20/20 to no light perception. All patients received immunosuppressive therapy including cyclosporine and anti-thymocyte globulin, and two underwent hematopoietic stem cell transplantation. All patients received perioperative platelet and blood transfusions. Pars plana vitrectomy resulted in functional and anatomic success in the majority of eyes in this series. Coordination of medical and surgical care with the hematology service is advisable to stabilize hematologic parameters prior to undertaking a vitreoretinal procedure.<br /> (Copyright 2010, SLACK Incorporated.)
- Subjects :
- Antilymphocyte Serum therapeutic use
Child, Preschool
Choroid blood supply
Eye Diseases pathology
Eye Diseases physiopathology
Eye Diseases therapy
Follow-Up Studies
Fundus Oculi
Humans
Ischemia etiology
Male
Retinal Neovascularization etiology
Treatment Outcome
Visual Acuity
Vitrectomy methods
Vitreous Hemorrhage etiology
Young Adult
Anemia, Aplastic complications
Eye Diseases etiology
Posterior Eye Segment
Subjects
Details
- Language :
- English
- ISSN :
- 1938-2375
- Volume :
- 41 Online
- Database :
- MEDLINE
- Journal :
- Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye
- Publication Type :
- Academic Journal
- Accession number :
- 20806744
- Full Text :
- https://doi.org/10.3928/15428877-20100625-04