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The utility of F-18 FDG PET/CT in the evaluation of pancreatic intraductal papillary mucinous neoplasm.
- Source :
-
Clinical nuclear medicine [Clin Nucl Med] 2010 Oct; Vol. 35 (10), pp. 776-9. - Publication Year :
- 2010
-
Abstract
- Purpose: To assess the utility of F-18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) in evaluating pancreatic intraductal papillary mucinous neoplasm (IPMN).<br />Materials and Methods: We included 31 patients with pancreatic IPMN who underwent F-18 FDG PET/CT and multidetector CT (MDCT). Each pancreatic lesion was classified as benign or malignant. On PET, the maximal standardized uptake value was measured in each pancreatic lesion.<br />Results: PET/CT was superior to MDCT in diagnosing malignant IPMN. All 22 concordant results gave accurate diagnoses. Of 9 discordant results, MDCT misdiagnosed 7 IPMNs, whereas PET/CT misinterpreted 2. Malignant IPMNs showed significantly higher maximal standardized uptake values (mean ± standard deviation, 6.7 ± 3.6) than benign IPMNs (mean ± standard deviation, 2.1 ± 1.0) (P < 0.001).<br />Conclusions: F-18 FDG PET/CT outperformed MDCT in detecting malignant IPMN.
- Subjects :
- Aged
Biological Transport
Female
Humans
Male
Middle Aged
Neoplasms, Cystic, Mucinous, and Serous metabolism
Pancreatic Neoplasms metabolism
Retrospective Studies
Fluorodeoxyglucose F18 metabolism
Neoplasms, Cystic, Mucinous, and Serous diagnostic imaging
Pancreatic Neoplasms diagnostic imaging
Positron-Emission Tomography
Tomography, X-Ray Computed
Subjects
Details
- Language :
- English
- ISSN :
- 1536-0229
- Volume :
- 35
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Clinical nuclear medicine
- Publication Type :
- Academic Journal
- Accession number :
- 20838285
- Full Text :
- https://doi.org/10.1097/RLU.0b013e3181e4da32