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Magnetic resonance imaging at 3.0T for submandibular gland sparing radiotherapy.
- Source :
-
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology [Radiother Oncol] 2010 Nov; Vol. 97 (2), pp. 239-43. Date of Electronic Publication: 2010 Sep 16. - Publication Year :
- 2010
-
Abstract
- Purpose: Besides sparing the parotid gland, sparing the submandibular gland is considered to be important in preventing xerostomia in head-and-neck cancer patients. Delineation of the submandibular gland at CT, and even on T(1)- and T(2)-weighted MR images, is difficult, due to low contrast with the surrounding tissues. MR sialography might be used for delineation.<br />Methods and Materials: Sixteen oropharyngeal cancer patients received a CT and MRI exam as part of the standard treatment imaging protocol. Patients were scanned in their five-point RT immobilization mask. The MRI exam included T(1)- and T(2)-weighted MRI scans and an MR sialography scan. Thirty submandibular glands were delineated on only CT, on the combined CT and T(1)- and T(2)-weighted MRI scans and on all MR images. A Wilcoxon signed-rank test was performed to test if the delineated volumes were significantly different.<br />Results: The delineated volume of the submandibular gland was 7.3mL in the CT-delineation, 7.1mL in the CT/MRI-delineation and 8.1mL in the MRI-delineation. The MRI-delineation was significantly larger than the other delineations (p<0.001). The differences were mainly located in the cranial direction.<br />Conclusion: The delineation of the submandibular gland was improved in the cranial direction by using T(1)- and T(2)-weighted MRI and MR sialography, compared to the other delineations.<br /> (Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1879-0887
- Volume :
- 97
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
- Publication Type :
- Academic Journal
- Accession number :
- 20846735
- Full Text :
- https://doi.org/10.1016/j.radonc.2010.08.014