[Plasma fibronectin in experimental combined mechanical trauma, complicated by disseminated intravascular coagulation].

Hemocoagulation system state and plasmatic fibronectin level at experimental associated craniocerebral trauma have been studied at 29 mongrel white rats (males). It has been revealed that associated craniocerebral trauma, complicated by disseminated intravascular blood coagulation, is accompanied by reliable decrease of plasmatic fibronectin concentration. It has been established that hypofibronectinemia has temporal coincidence with the reaction of hemocoagulation system on trauma and direct quantitative correlation with the decrease of coagulating fibrinogen level and fibrinolytic system activation.