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Relationship between obstructive coronary artery disease and abnormal stress testing in patients with paroxysmal or persistent atrial fibrillation.
- Source :
-
The international journal of cardiovascular imaging [Int J Cardiovasc Imaging] 2011 Jul; Vol. 27 (6), pp. 777-85. Date of Electronic Publication: 2010 Oct 16. - Publication Year :
- 2011
-
Abstract
- Atrial fibrillation (AF) has been linked to the presence of underlying coronary artery disease (CAD). However, whether the higher burden of CAD observed in AF patients translates into higher burden of myocardial ischemia is unknown. In 87 patients (71% male, mean age 61 ± 10 years) with paroxysmal or persistent AF and without history of CAD, MSCT coronary angiography and stress testing (exercise ECG test or myocardial perfusion imaging) were performed. CAD was classified as obstructive (≥50% luminal narrowing) or not. Stress tests were classified as normal or abnormal. A population of 122 patients without history of AF, similar to the AF group as to age, gender, symptomatic status and pre-test likelihood, served as a control group. Based on MSCT, 17% of AF patients were classified as having no CAD, whereas 43% showed non-obstructive CAD and the remaining 40% had obstructive CAD. A positive stress test was observed in 49% of AF patients with obstructive CAD. Among non-AF patients, 34% were classified as having no CAD, while 41% showed non-obstructive CAD and 25% had obstructive CAD (P = 0.013 compared to AF patients). A positive stress test was observed in 48% of non-AF patients with obstructive CAD. In conclusion, the higher burden of CAD observed in AF patients is not associated to higher burden of myocardial ischemia.
- Subjects :
- Aged
Atrial Fibrillation epidemiology
Case-Control Studies
Chi-Square Distribution
Coronary Stenosis epidemiology
Europe epidemiology
Female
Humans
Male
Middle Aged
Myocardial Ischemia epidemiology
Predictive Value of Tests
Prevalence
Risk Assessment
Risk Factors
Severity of Illness Index
Atrial Fibrillation diagnosis
Coronary Angiography
Coronary Stenosis diagnosis
Electrocardiography
Exercise Test
Myocardial Ischemia diagnosis
Myocardial Perfusion Imaging
Subjects
Details
- Language :
- English
- ISSN :
- 1875-8312
- Volume :
- 27
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- The international journal of cardiovascular imaging
- Publication Type :
- Academic Journal
- Accession number :
- 20953841
- Full Text :
- https://doi.org/10.1007/s10554-010-9725-x