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Sentinel lymph node biopsy and management of the axilla in ductal carcinoma in situ.
- Source :
-
Journal of the National Cancer Institute. Monographs [J Natl Cancer Inst Monogr] 2010; Vol. 2010 (41), pp. 145-9. - Publication Year :
- 2010
-
Abstract
- Ductal carcinoma in situ (DCIS) of the breast historically has been a disease detected by physical examination, diagnosed by open surgical biopsy, and treated by mastectomy and axillary dissection. It is now increasingly detected by screening mammography, diagnosed by needle core biopsy, and treated by lumpectomy, with axillary dissection having been abandoned and sentinel node biopsy being used in axillary staging. However, outcomes related to sentinel node biopsy in DCIS have not been validated in well-controlled clinical trials. Current guideline recommendations are to use sentinel node biopsy when needle core biopsy is highly suspicious for invasive cancer or where there is a high-risk DCIS when lumpectomy identifies invasive breast cancer with the DCIS, or when mastectomy is performed for extensive DCIS. Routine use of sentinel node biopsy for DCIS is not supported.
- Subjects :
- Adult
Axilla
Breast Neoplasms diagnostic imaging
Breast Neoplasms radiotherapy
Breast Neoplasms surgery
Carcinoma, Intraductal, Noninfiltrating diagnostic imaging
Carcinoma, Intraductal, Noninfiltrating radiotherapy
Carcinoma, Intraductal, Noninfiltrating surgery
Combined Modality Therapy
Female
Humans
Lymphatic Metastasis
Magnetic Resonance Imaging methods
Mammography
Mastectomy methods
Middle Aged
Multicenter Studies as Topic statistics & numerical data
Neoplasm Invasiveness
Neoplasm Staging
Radiotherapy, Adjuvant
Randomized Controlled Trials as Topic statistics & numerical data
Risk
Sensitivity and Specificity
Treatment Outcome
Unnecessary Procedures
Breast Neoplasms pathology
Carcinoma, Intraductal, Noninfiltrating secondary
Lymph Node Excision
Sentinel Lymph Node Biopsy adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 1745-6614
- Volume :
- 2010
- Issue :
- 41
- Database :
- MEDLINE
- Journal :
- Journal of the National Cancer Institute. Monographs
- Publication Type :
- Academic Journal
- Accession number :
- 20956820
- Full Text :
- https://doi.org/10.1093/jncimonographs/lgq026