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Adaptation of a novel operant orofacial testing system to characterize both mechanical and thermal pain.

Authors :
Nolan TA
Hester J
Bokrand-Donatelli Y
Caudle RM
Neubert JK
Source :
Behavioural brain research [Behav Brain Res] 2011 Mar 01; Vol. 217 (2), pp. 477-80. Date of Electronic Publication: 2010 Oct 23.
Publication Year :
2011

Abstract

Mechanical pain sensitivity is characteristic of many orofacial pain conditions; however, few models exist to quantify this pain. Here we evaluated a novel adaptation of our existing operant system to characterize orofacial pain following mechanical and thermal stimuli. We demonstrate that the operant system is able to detect painful and analgesic responses to mechanical stimuli. These findings allow comparison of both mechanical and thermal stimuli using the same outcome measures.<br /> (Copyright © 2010 Elsevier B.V. All rights reserved.)

Details

Language :
English
ISSN :
1872-7549
Volume :
217
Issue :
2
Database :
MEDLINE
Journal :
Behavioural brain research
Publication Type :
Academic Journal
Accession number :
20974188
Full Text :
https://doi.org/10.1016/j.bbr.2010.10.022