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[Alkylglycerolipids--modulators of tumor cells death].
- Source :
-
Biomeditsinskaia khimiia [Biomed Khim] 2010 Jul-Aug; Vol. 56 (4), pp. 457-70. - Publication Year :
- 2010
-
Abstract
- The review is summarizes current information on biological activity and search of the antineoplastic mechanism of action of alkyl glycerolipids. Special attention is paid to following problems: selective ability phosphorus alkyl glycerolipids, antineoplastic activity, cytostatic and cytotoxic effects of edelfosine and its analogues. The review contains set of the data known for today from the literature, on the possible mechanism cytoyoxic actions of such connections.
- Subjects :
- Animals
Antineoplastic Agents chemistry
Caspases physiology
Cell Death
Humans
Membrane Microdomains physiology
Phospholipid Ethers chemistry
Receptors, Tumor Necrosis Factor physiology
Signal Transduction
fas Receptor physiology
Antineoplastic Agents pharmacology
Phospholipid Ethers pharmacology
Subjects
Details
- Language :
- Russian
- ISSN :
- 2310-6972
- Volume :
- 56
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Biomeditsinskaia khimiia
- Publication Type :
- Academic Journal
- Accession number :
- 21032896