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Correlation between serum and plasma antibody titers to mycobacterial antigens.
- Source :
-
Clinical and vaccine immunology : CVI [Clin Vaccine Immunol] 2011 Jan; Vol. 18 (1), pp. 173-5. Date of Electronic Publication: 2010 Nov 03. - Publication Year :
- 2011
-
Abstract
- The ability to utilize serum or plasma samples interchangeably is useful for tuberculosis (TB) serology. We demonstrate a strong correlation between antibody titers to several mycobacterial antigens in serum versus plasma from HIV-infected and non-HIV-infected TB and non-TB patients (r = 0.99 to 0.89; P < 0.0001). Plasma and serum can be used interchangeably in the same antibody detection assays.
- Subjects :
- Adult
Bacterial Proteins immunology
Female
HIV Infections complications
HIV Infections immunology
Humans
Malate Synthase immunology
Male
Mannans immunology
Middle Aged
Tuberculosis complications
Tuberculosis immunology
Antibodies, Bacterial blood
Antigens, Bacterial immunology
Mycobacterium bovis immunology
Mycobacterium tuberculosis immunology
Plasma immunology
Serum immunology
Subjects
Details
- Language :
- English
- ISSN :
- 1556-679X
- Volume :
- 18
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Clinical and vaccine immunology : CVI
- Publication Type :
- Academic Journal
- Accession number :
- 21047999
- Full Text :
- https://doi.org/10.1128/CVI.00325-10