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Head and neck osteosarcoma.
- Source :
-
American journal of otolaryngology [Am J Otolaryngol] 2011 Nov-Dec; Vol. 32 (6), pp. 597-600. Date of Electronic Publication: 2010 Nov 19. - Publication Year :
- 2011
-
Abstract
- Objective: The objective of the study was to discuss the optimal management and treatment outcomes for patients with head and neck osteosarcomas.<br />Study Design: Review article.<br />Methods: Review of the pertinent literature.<br />Results: Osteosarcomas account for approximately 1% or less of all head and neck cancers. The vast majority occur in the mandible and maxilla. The median age is in the fourth decade, with a wide range. They are more likely to recur locally after treatment and distant metastases are observed less often than with the more common osteosarcomas arising in the long bones. The optimal treatment is complete resection. The role of adjuvant chemotherapy is ill-defined. The vast majority of recurrences are observed within 5 years. The 5-year disease-specific and overall survival rates are approximately 60% to 70%.<br />Conclusions: Osteosarcoma of the head and neck is a rare entity that occurs primarily in the mandible and maxilla. The optimal treatment is surgery. Adjuvant radiotherapy should be considered for those with close or positive margins. The role of adjuvant chemotherapy is ill-defined. The likelihood of cure is approximately 60% to 70%.<br /> (Copyright © 2011 Elsevier Inc. All rights reserved.)
- Subjects :
- Age Distribution
Disease-Free Survival
Female
Head and Neck Neoplasms pathology
Head and Neck Neoplasms radiotherapy
Humans
Incidence
Male
Neck Dissection methods
Neoplasm Invasiveness pathology
Neoplasm Staging
Osteosarcoma pathology
Prognosis
Radiotherapy, Adjuvant
Risk Assessment
Sex Distribution
Survival Analysis
Treatment Outcome
Head and Neck Neoplasms mortality
Head and Neck Neoplasms surgery
Osteosarcoma epidemiology
Osteosarcoma surgery
Subjects
Details
- Language :
- English
- ISSN :
- 1532-818X
- Volume :
- 32
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- American journal of otolaryngology
- Publication Type :
- Academic Journal
- Accession number :
- 21093108
- Full Text :
- https://doi.org/10.1016/j.amjoto.2010.09.002