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Rett syndrome diagnostic criteria: lessons from the Natural History Study.
- Source :
-
Annals of neurology [Ann Neurol] 2010 Dec; Vol. 68 (6), pp. 951-5. - Publication Year :
- 2010
-
Abstract
- Analysis of 819 participants enrolled in the Rett syndrome (RTT) Natural History Study validates recently revised diagnostic criteria. 765 females fulfilled 2002 consensus criteria for classic (653/85.4%) or variant (112/14.6%) RTT. All participants classified as classic RTT fulfilled each revised main criterion; supportive criteria were not uniformly present. All variant RTT participants met at least 3 of 6 main criteria in the 2002, 2 of 4 main criteria in the current format, and 5 of 11 supportive criteria in both. This analysis underscores the critical role of main criteria for classic RTT; variant RTT requires both main and supportive criteria.
Details
- Language :
- English
- ISSN :
- 1531-8249
- Volume :
- 68
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Annals of neurology
- Publication Type :
- Academic Journal
- Accession number :
- 21104896
- Full Text :
- https://doi.org/10.1002/ana.22154