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Adipose-derived stem cells for myocardial infarction.

Authors :
Mazo M
Gavira JJ
Pelacho B
Prosper F
Source :
Journal of cardiovascular translational research [J Cardiovasc Transl Res] 2011 Apr; Vol. 4 (2), pp. 145-53. Date of Electronic Publication: 2010 Nov 30.
Publication Year :
2011

Abstract

In recent years, stem cell treatment of myocardial infarction has elicited great enthusiasm upon scientists and physicians alike, thus making the finding of a suitable cell a compulsory subject for modern medicine. Due to its potential, accessibility and efficiency of harvesting, adipose tissue has become one of the most attractive sources of stem cells for regenerative therapies. The differentiation capacity and the paracrine activity of these cells has made them an optimal candidate for the treatment of a diverse range of diseases from immunological disorders as graft versus host disease to cardiovascular pathologies like peripheral ischemia. In this review, we will focus on the use of stem cells derived from adipose tissue for treatment of myocardial infarction, with special attention to their putative in vivo mechanisms of action.

Details

Language :
English
ISSN :
1937-5395
Volume :
4
Issue :
2
Database :
MEDLINE
Journal :
Journal of cardiovascular translational research
Publication Type :
Academic Journal
Accession number :
21116883
Full Text :
https://doi.org/10.1007/s12265-010-9246-y