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Adipose-derived stem cells for myocardial infarction.
- Source :
-
Journal of cardiovascular translational research [J Cardiovasc Transl Res] 2011 Apr; Vol. 4 (2), pp. 145-53. Date of Electronic Publication: 2010 Nov 30. - Publication Year :
- 2011
-
Abstract
- In recent years, stem cell treatment of myocardial infarction has elicited great enthusiasm upon scientists and physicians alike, thus making the finding of a suitable cell a compulsory subject for modern medicine. Due to its potential, accessibility and efficiency of harvesting, adipose tissue has become one of the most attractive sources of stem cells for regenerative therapies. The differentiation capacity and the paracrine activity of these cells has made them an optimal candidate for the treatment of a diverse range of diseases from immunological disorders as graft versus host disease to cardiovascular pathologies like peripheral ischemia. In this review, we will focus on the use of stem cells derived from adipose tissue for treatment of myocardial infarction, with special attention to their putative in vivo mechanisms of action.
- Subjects :
- Animals
Cell Differentiation
Humans
Myocardial Infarction metabolism
Myocardial Infarction pathology
Myocardial Infarction physiopathology
Myocardium metabolism
Myocytes, Cardiac metabolism
Paracrine Communication
Recovery of Function
Regeneration
Treatment Outcome
Adipose Tissue cytology
Myocardial Infarction surgery
Myocardium pathology
Myocytes, Cardiac transplantation
Stem Cell Transplantation
Subjects
Details
- Language :
- English
- ISSN :
- 1937-5395
- Volume :
- 4
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Journal of cardiovascular translational research
- Publication Type :
- Academic Journal
- Accession number :
- 21116883
- Full Text :
- https://doi.org/10.1007/s12265-010-9246-y