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[Stage 1 testicular seminoma].
- Source :
-
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique [Cancer Radiother] 2010 Nov; Vol. 14 Suppl 1, pp. S182-8. - Publication Year :
- 2010
-
Abstract
- Testicular cancer is rare, representing only 1 % of malignant tumors, but the most common cancer in young men, 15 to 35 years. Adjuvant radiotherapy after orchidectomy in testicular seminoma stage I, reduces risk of relapse. It aims to eradicate micro-metastatic disease in lymph drainage territories. In the case of adjuvant radiotherapy, the relapse-free survival of 96 % with an overall survival of 98 % at 5 years. The irradiation volume is made up of lymph nodes paraaortic which it is possible to add the ipsilateral renal hilum to the testicular lesion. The current recommended dose is 20 Gy in 10 fractions and 2 weeks, usually delivered by two antero-posterior beams. The acute toxicities, mainly represented by nausea and diarrhea are usually quickly resolved to the end of irradiation. Regarding toxicities long-term, preservation of semen should be considered after surgery because of fear of infertility post-treatment. The risk of second cancer associated with exposure to ionizing radiation, albeit small, is especially important to consider these patients to significant life expectancy. Nevertheless, developments in radiotherapy techniques and lower doses and irradiated volumes can probably reduce this risk further.<br /> (Copyright © 2010 Elsevier Masson SAS. All rights reserved.)
- Subjects :
- Adolescent
Adult
Diarrhea diagnostic imaging
Disease-Free Survival
Dose Fractionation, Radiation
Humans
Incidence
Lymph Nodes parasitology
Lymph Nodes radiation effects
Male
Nausea diagnostic imaging
Radionuclide Imaging
Radiotherapy adverse effects
Radiotherapy methods
Radiotherapy Dosage
Seminoma epidemiology
Seminoma pathology
Seminoma surgery
Testicular Neoplasms epidemiology
Testicular Neoplasms pathology
Testicular Neoplasms surgery
Young Adult
Seminoma radiotherapy
Testicular Neoplasms radiotherapy
Subjects
Details
- Language :
- French
- ISSN :
- 1769-6658
- Volume :
- 14 Suppl 1
- Database :
- MEDLINE
- Journal :
- Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
- Publication Type :
- Academic Journal
- Accession number :
- 21129662
- Full Text :
- https://doi.org/10.1016/S1278-3218(10)70022-6