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Efficacy of three surface disinfectants against spores of Clostridium difficile ribotype 027.
- Source :
-
International journal of hygiene and environmental health [Int J Hyg Environ Health] 2011 Mar; Vol. 214 (2), pp. 172-4. Date of Electronic Publication: 2010 Dec 04. - Publication Year :
- 2011
-
Abstract
- Background: The emergence of Clostridium difficile ribotype 027 raised the question of sporicidal surface disinfectants are also effective against spores of C. difficile ribotype 027.<br />Materials and Methods: Three surface disinfectants based on magnesium monoperoxyphthalate hexahydrate (Dismozon pur), a combination of (ethylenedioxy)dimethanol, glutaral and benzyl-C12-18-alkyldimethylammonium chlorides (Kohrsolin extra) and a combination of glutaral, benzyl-C12-18-alkyldimethylammonium chlorides and didecyl-dimethylammonium chloride (Kohrsolin FF) were tested in a suspension test in various concentrations and contact times against spores of three C. difficile strains including ribotype 027.<br />Results: All three surface disinfectant reduced the number of spores by ≥4 log(10) steps, e.g. Dismozon pur at 1.5% and 2 h exposure time, Kohrsolin extra at 2% and 4 h exposure time, and Kohrsolin FF at 2% and 6 h exposure time. Spores of ribotype 027 did not show a lower susceptibility to Dismozon pur compared to the other two C. difficile strains.<br />Conclusions: All three tested surface disinfectants should be effective for surface disinfection in outbreaks caused by C. difficile ribotype 027.<br /> (Copyright © 2010 Elsevier GmbH. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1618-131X
- Volume :
- 214
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- International journal of hygiene and environmental health
- Publication Type :
- Academic Journal
- Accession number :
- 21134785
- Full Text :
- https://doi.org/10.1016/j.ijheh.2010.10.004