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Efficacy of three surface disinfectants against spores of Clostridium difficile ribotype 027.

Authors :
Horejsh D
Kampf G
Source :
International journal of hygiene and environmental health [Int J Hyg Environ Health] 2011 Mar; Vol. 214 (2), pp. 172-4. Date of Electronic Publication: 2010 Dec 04.
Publication Year :
2011

Abstract

Background: The emergence of Clostridium difficile ribotype 027 raised the question of sporicidal surface disinfectants are also effective against spores of C. difficile ribotype 027.<br />Materials and Methods: Three surface disinfectants based on magnesium monoperoxyphthalate hexahydrate (Dismozon pur), a combination of (ethylenedioxy)dimethanol, glutaral and benzyl-C12-18-alkyldimethylammonium chlorides (Kohrsolin extra) and a combination of glutaral, benzyl-C12-18-alkyldimethylammonium chlorides and didecyl-dimethylammonium chloride (Kohrsolin FF) were tested in a suspension test in various concentrations and contact times against spores of three C. difficile strains including ribotype 027.<br />Results: All three surface disinfectant reduced the number of spores by ≥4 log(10) steps, e.g. Dismozon pur at 1.5% and 2 h exposure time, Kohrsolin extra at 2% and 4 h exposure time, and Kohrsolin FF at 2% and 6 h exposure time. Spores of ribotype 027 did not show a lower susceptibility to Dismozon pur compared to the other two C. difficile strains.<br />Conclusions: All three tested surface disinfectants should be effective for surface disinfection in outbreaks caused by C. difficile ribotype 027.<br /> (Copyright © 2010 Elsevier GmbH. All rights reserved.)

Details

Language :
English
ISSN :
1618-131X
Volume :
214
Issue :
2
Database :
MEDLINE
Journal :
International journal of hygiene and environmental health
Publication Type :
Academic Journal
Accession number :
21134785
Full Text :
https://doi.org/10.1016/j.ijheh.2010.10.004