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Acid-catalyzed synthesis of bicyclo[3.n.1]alkenediones.

Authors :
Michaelides IN
Darses B
Dixon DJ
Source :
Organic letters [Org Lett] 2011 Feb 18; Vol. 13 (4), pp. 664-7. Date of Electronic Publication: 2011 Jan 19.
Publication Year :
2011

Abstract

An acid-catalyzed Dieckmann-type reaction has been developed to access functionalized bicyclo[3.2.1]alkenediones. This methodology has been successfully extended to more substituted and larger ring homologues, providing a new and efficient route to the core of numerous attractive natural products and their analogues.

Details

Language :
English
ISSN :
1523-7052
Volume :
13
Issue :
4
Database :
MEDLINE
Journal :
Organic letters
Publication Type :
Academic Journal
Accession number :
21247086
Full Text :
https://doi.org/10.1021/ol102909t