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Synthetic approaches to the 2009 new drugs.

Authors :
Liu KK
Sakya SM
O'Donnell CJ
Flick AC
Li J
Source :
Bioorganic & medicinal chemistry [Bioorg Med Chem] 2011 Feb 01; Vol. 19 (3), pp. 1136-54. Date of Electronic Publication: 2010 Dec 24.
Publication Year :
2011

Abstract

New drugs are introduced to the market every year and each individual drug represents a privileged structure for its biological target. These new chemical entities (NCEs) provide insights into molecular recognition and also serve as leads for designing future new drugs. This review covers the syntheses of 21 NCEs marketed in 2009.<br /> (Copyright © 2011 Elsevier Ltd. All rights reserved.)

Details

Language :
English
ISSN :
1464-3391
Volume :
19
Issue :
3
Database :
MEDLINE
Journal :
Bioorganic & medicinal chemistry
Publication Type :
Academic Journal
Accession number :
21256756
Full Text :
https://doi.org/10.1016/j.bmc.2010.12.038