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[Diversity of incidence trend patterns: implications for carcinogenesis?].
- Source :
-
Revue des maladies respiratoires [Rev Mal Respir] 2011 Jan; Vol. 28 (1), pp. 41-50. Date of Electronic Publication: 2011 Jan 03. - Publication Year :
- 2011
-
Abstract
- Objective: Cancers of the ENT, oesophagus and lungs are caused mainly by alcohol and/or tobacco consumption but have potentially heterogeneous latencies and dose-incidence relationships. The incidence of cancers having the same risk factors may vary in a similar way over time and space. The aim of the study was to identify groups of cancers with similar spatio-temporal incidence trends.<br />Methods: Fifty thousand nine hundred and eighty cases of ten cancer types were collected between 1982 and 2002 in six French departments. The incidence levels and trends were assessed using an age-cohort random-effect model that took into account heterogeneity of incidence levels and trends between departments.<br />Results: Three groups of cancer sites/types with similar spatio-temporal incidence trends were identified: (1) oral cavity, oropharynx, hypopharynx, larynx, oesophagus, and lung squamous cell carcinomas in which the incidence decreased similarly in time and space; (2) other types of lung cancer and lung adenocarcinomas whose incidence increased similarly; and (3) lung large- and small-cell carcinomas whose incidence trends were heterogeneous.<br />Conclusion: Using the tools of descriptive epidemiology different cancer groups with different temporal and spatial incidence trends were identified. This diversity suggests different latencies and different sensitivities of those groups to the main risk factors, alcohol and tobacco.<br /> (Copyright © 2010 SPLF. Published by Elsevier Masson SAS. All rights reserved.)
- Subjects :
- Adenocarcinoma diagnosis
Adenocarcinoma epidemiology
Adenocarcinoma etiology
Adenocarcinoma pathology
Adult
Aged
Aged, 80 and over
Alcohol Drinking adverse effects
Alcohol Drinking epidemiology
Carcinoma, Non-Small-Cell Lung diagnosis
Carcinoma, Non-Small-Cell Lung epidemiology
Carcinoma, Non-Small-Cell Lung etiology
Carcinoma, Non-Small-Cell Lung pathology
Carcinoma, Small Cell diagnosis
Carcinoma, Small Cell epidemiology
Carcinoma, Small Cell etiology
Carcinoma, Small Cell pathology
Carcinoma, Squamous Cell diagnosis
Carcinoma, Squamous Cell epidemiology
Carcinoma, Squamous Cell etiology
Carcinoma, Squamous Cell pathology
Cross-Sectional Studies
Esophageal Neoplasms diagnosis
Esophageal Neoplasms epidemiology
Esophageal Neoplasms etiology
Esophageal Neoplasms pathology
Female
France
Humans
Incidence
Lung Neoplasms diagnosis
Lung Neoplasms epidemiology
Lung Neoplasms etiology
Lung Neoplasms pathology
Male
Middle Aged
Otorhinolaryngologic Neoplasms diagnosis
Otorhinolaryngologic Neoplasms pathology
Registries statistics & numerical data
Risk Factors
Smoking adverse effects
Smoking epidemiology
Otorhinolaryngologic Neoplasms epidemiology
Otorhinolaryngologic Neoplasms etiology
Subjects
Details
- Language :
- French
- ISSN :
- 1776-2588
- Volume :
- 28
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Revue des maladies respiratoires
- Publication Type :
- Academic Journal
- Accession number :
- 21277473
- Full Text :
- https://doi.org/10.1016/j.rmr.2010.12.002