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Repeat low-grade squamous intraepithelial cytology with unsatisfactory colposcopy treated by the loop electrosurgical excision procedure: a retrospective study.
- Source :
-
European journal of gynaecological oncology [Eur J Gynaecol Oncol] 2010; Vol. 31 (6), pp. 632-5. - Publication Year :
- 2010
-
Abstract
- Investigation: To evaluate the value of the loop electrosurgical excision procedure (LEEP) for repeat low-grade squamous intraepithelial lesions (LSIL) with unsatisfactory colposcopy and the outcomes of postconization.<br />Methods: We performed LEEP in 136 patients and followed them up with colposcopy, cytology, and high-risk HPV (HR-HPV) detection using Hybrid Capture II (HCII).<br />Results: 55.1% of women had CIN 1 in the specimen, 17.6% had CIN 2-3, and 27.2% had no lesion. The sensitivity of detecting persistent/recurrent disease can reach 90.9% when positive post-treatment HR-HPV or first abnormal cervical cytology after LEEP are found, and the specificity is 95.3% when positive post-treatment HR-HPV coexisting with first abnormal cervical cytology after LEEP are detected.<br />Conclusion: Repeat LSIL with unsatisfactory colposcopy implies a significant risk of CIN 2-3. LEEP is a rational option to those patients with high-risk HPV infection or dysplastic endocervical curettage. Post-treatment follow-up of patients should include both cytology and HR-HPV testing.
- Subjects :
- Adult
China
Colposcopy methods
Female
Follow-Up Studies
Gynecologic Surgical Procedures methods
Humans
Middle Aged
Neoplasm Recurrence, Local pathology
Neoplasm Staging
Retrospective Studies
Treatment Outcome
Uterine Cervical Neoplasms surgery
Women's Health
Uterine Cervical Dysplasia pathology
Colposcopy adverse effects
Electrosurgery methods
Neoplasm Recurrence, Local surgery
Uterine Cervical Neoplasms pathology
Uterine Cervical Dysplasia surgery
Subjects
Details
- Language :
- English
- ISSN :
- 0392-2936
- Volume :
- 31
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- European journal of gynaecological oncology
- Publication Type :
- Academic Journal
- Accession number :
- 21319505