Back to Search
Start Over
A case of recovery from canine destructive cholangitis in a Miniature Dachshund.
- Source :
-
The Journal of veterinary medical science [J Vet Med Sci] 2011 Jul; Vol. 73 (7), pp. 937-9. Date of Electronic Publication: 2011 Feb 14. - Publication Year :
- 2011
-
Abstract
- A 7-year-old Miniature Dachshund presented with severe chronic jaundice and elevated liver enzymes. Destructive cholangitis was diagnosed according to histopathological findings of remarkable ductopenia with inflammatory infiltrates and fibrosis in the portal areas. Supportive therapy with prednisolone, high-dose ursodeoxycholic acid, human placental extract and antibiotics was tried, and the patient showed recovery of clinical signs 3 months after diagnosis. A second liver biopsy was performed about 1 year after initial diagnosis, and bile duct restoration was confirmed with continuous inflammation around portal areas and inside the lobules. Although we could not determine which treatment was effective in this case, destructive cholangitis in dogs may be recoverable with long-term supportive therapies.
- Subjects :
- Animals
Anti-Bacterial Agents therapeutic use
Biopsy veterinary
Cholangitis diagnostic imaging
Cholangitis drug therapy
Cholangitis pathology
Dog Diseases diagnostic imaging
Dog Diseases pathology
Dogs
Histocytochemistry veterinary
Male
Placental Extracts therapeutic use
Prednisolone therapeutic use
Ultrasonography
Ursodeoxycholic Acid therapeutic use
Cholangitis veterinary
Dog Diseases drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1347-7439
- Volume :
- 73
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- The Journal of veterinary medical science
- Publication Type :
- Academic Journal
- Accession number :
- 21325741
- Full Text :
- https://doi.org/10.1292/jvms.10-0448