Back to Search
Start Over
[Prognosis of patients with recurrence after curative resection of advanced gastric cancer].
- Source :
-
Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery [Zhonghua Wei Chang Wai Ke Za Zhi] 2011 Feb; Vol. 14 (2), pp. 107-10. - Publication Year :
- 2011
-
Abstract
- Objective: To investigate the clinical features and prognosis of recurrent gastric cancer.<br />Methods: Clinical data of 163 patients with recurrent gastric cancer from Jan. 2001 to Jan. 2005 were reviewed. Patients were compared between those with and without symptoms.<br />Results: Seventy-two patients(44.2%) were symptomatic, while 91(55.8%) were asymptomatic. There were significant differences in lymph node metastasis between the two groups(P<0.05). The median overall survival was significantly longer in asymptomatic patients (19.8 vs. 15.7 months, P<0.05). Post-recurrence survival was also longer in the asymptomatic group (9.5 vs. 4.8 months, P<0.01). The median recurrence-free interval in asymptomatic patients was 10.0 months, which was significantly longer than that in the symptomatic patients (9.2 months, P<0.05). On univariate survival analysis,post-gastrectomy chemotherapy (P<0.05), symptoms of recurrence(P<0.01), TNM staging(P<0.01), recurrence-free interval (P<0.01), and reoperation(P<0.01) were associated with the prognosis. On multivariable analysis, TNM staging(P<0.01), symptoms of recurrence(P<0.01), recurrence-free interval (P<0.05), and reoperation(P<0.05) were independent risk factors.<br />Conclusions: Patients with recurrent gastric cancer have poor prognosis. Close monitoring and active follow-up of patients with gastric cancer should be conducted during the first two years after operation. Reoperation may improve survival in patients with recurrent gastric cancer.
Details
- Language :
- Chinese
- ISSN :
- 1671-0274
- Volume :
- 14
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
- Publication Type :
- Academic Journal
- Accession number :
- 21365501