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Tissue distribution and appearance in ontogeny of alpha/beta T cell receptor (TCR2) in chicken.
- Source :
-
Cellular immunology [Cell Immunol] 1990 Jan; Vol. 125 (1), pp. 254-60. - Publication Year :
- 1990
-
Abstract
- We have performed immunoperoxidase staining on cryostat tissue sections and immunofluorescence analysis on cell suspensions to identify cells expressing the alpha/beta T cell antigen receptor during ontogeny and adult life in chickens. We used the mouse monoclonal antibody, TCR2, which was previously shown to recognize the alpha/beta TCR in chickens. TCR2+ cells were observed in thymic cortex and medulla and in T-dependent areas of spleen, intestine, and cecal tonsils of young adult chickens. Some TCR2+ cells were found in the cortex of bursal follicles and in liver. The first TCR2+ cells appear in thymus on Day 13 of the embryonic life and it is only after hatching that TCR2+ cells begin to migrate to the periphery.
- Subjects :
- Age Factors
Animals
Chick Embryo
Immunoenzyme Techniques
Receptors, Antigen, T-Cell, alpha-beta
Spleen embryology
Spleen immunology
T-Lymphocytes metabolism
Thymus Gland embryology
Thymus Gland immunology
Tissue Distribution
Chickens immunology
Receptors, Antigen, T-Cell metabolism
T-Lymphocytes immunology
Subjects
Details
- Language :
- English
- ISSN :
- 0008-8749
- Volume :
- 125
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Cellular immunology
- Publication Type :
- Academic Journal
- Accession number :
- 2136720
- Full Text :
- https://doi.org/10.1016/0008-8749(90)90079-7